Electroanalytical study of the interaction between dsDNA and curcumin in the presence of copper(II)

dc.contributor.author	Serpi C.
dc.contributor.author	Stanic, Zorka
dc.contributor.author	girousi, stella
dc.date.accessioned	2021-04-20T15:11:53Z
dc.date.available	2021-04-20T15:11:53Z
dc.date.issued	2010
dc.description.abstract	As a result of the reaction between curcumin (CC) and copper(II) the characteristic peak of curcumin at -1.0 V significantly increased, and the peak at -1.6 V disappeared. Curcumin forms complex with copper(II). The interaction between double stranded (ds) calf-thymus DNA and curcumin in the presence of Cu(II) was studied in solution, by differential pulse adsorptive transfer voltammetry using carbon paste electrode (CPE) and hanging mercury drop electrode (HMDE). Cu(II)-CC complex generated changes in calf-thymus DNA. The characteristic peak of dsDNA, due to the oxidation of guanine residues, decreased. The increased DNA damage by Cu(II)-CC complex was observed in the presence of various concentrations of the transition metal ions, copper(II). © 2010.
dc.identifier.doi	10.1016/j.talanta.2010.03.031
dc.identifier.issn	0039-9140
dc.identifier.scopus	2-s2.0-77952243452
dc.identifier.uri	https://scidar.kg.ac.rs/handle/123456789/10225
dc.rights	restrictedAccess
dc.source	Talanta
dc.title	Electroanalytical study of the interaction between dsDNA and curcumin in the presence of copper(II)
dc.type	article

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