Substituted imino and amino derivatives of 4-hydroxycoumarins as novel antioxidant, antibacterial and antifungal agents: Synthesis and in vitro assessments

dc.contributor.author	Vukovic, Nenad
dc.contributor.author	Sukdolak S.
dc.contributor.author	Solujic A.
dc.contributor.author	Martinović, Neda
dc.date.accessioned	2021-04-20T15:16:34Z
dc.date.available	2021-04-20T15:16:34Z
dc.date.issued	2010
dc.description.abstract	A series of imino and amino derivatives of 4-hydroxycoumarins were synthesised and evaluated for antioxidant potential, through different in vitro models such as (DPPH) free radical-scavenging activity, linoleic acid emulsion model system, reducing power assay and phosphomolybdenum method. Also, antimicrobial activity of obtained coumarins was evaluated against 13 bacteria and eight fungi. All prepared compounds possessed good antioxidant activity and among them a p-nitrophenol derivative with IC50 at 25.9 μM possessed radical-scavenging activity which was comparable to BHT. Observed data for antibacterial activity indicated strong activity of all tested amino derivatives, while imines showed better antifungal properties. © 2009 Elsevier Ltd. All rights reserved.
dc.identifier.doi	10.1016/j.foodchem.2009.11.040
dc.identifier.issn	0308-8146
dc.identifier.scopus	2-s2.0-75049086152
dc.identifier.uri	https://scidar.kg.ac.rs/handle/123456789/10256
dc.rights	restrictedAccess
dc.source	Food Chemistry
dc.title	Substituted imino and amino derivatives of 4-hydroxycoumarins as novel antioxidant, antibacterial and antifungal agents: Synthesis and in vitro assessments
dc.type	article

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