Stereospecific ligands and their complexes. Part XV. Synthesis, characterization and cytotoxicity of novel platinum(IV) complexes with some esters of ethylenediamine-N, N' N′ -di-S, S-(2,2′ -dibenzyl)acetic acid. Crystal structure of O, O′ -dipropyl-ethylenediamine -N, N′ -di-S, S-(2,2′ -dibenzyl)acetate dihydrochloride

dc.contributor.authorDimitrijević D.
dc.contributor.authorGlocrossed D Signović V.
dc.contributor.authorRadic G.
dc.contributor.authorGarcía-Granda, Santiago
dc.contributor.authorMenéndez-Taboada L.
dc.contributor.authorMilovanovic, Marija
dc.contributor.authorVolarevic, Vladislav
dc.contributor.authorArsenijevic, Nebojsa
dc.contributor.authorBogdanovic, Goran A.
dc.contributor.authorTrifunović, Srećko
dc.date.accessioned2021-04-20T15:45:13Z
dc.date.available2021-04-20T15:45:13Z
dc.date.issued2013
dc.description.abstractThe synthesis of ethylenediamine-N,N′'-di-S,S-(2,2′'-dibenzyl) acetic acid (H2-S,S-eddba) and its ethyl-, propyl-, butyl- esters (R2-S,S-eddba) are reported here. The esters were used for synthesis of the corresponding platinum(IV) complexes, [PtCl4(R 2-S,S-eddba)]. The compounds were characterized by elemental analysis, infrared, 1H and 13C NMR spectroscopy. The structure of propyl ester of H2-S,S-eddba was confirmed by single-crystal X-ray analysis. All [PtCl4(R2-S,S-eddba)] complexes displayed significantly higher in vitro cytotoxicity in comparison to cisplatin. © 2013 Published by Elsevier B.V.
dc.identifier.doi10.1016/j.ica.2013.03.039
dc.identifier.issn0020-1693
dc.identifier.scopus2-s2.0-84877087811
dc.identifier.urihttps://scidar.kg.ac.rs/handle/123456789/10438
dc.rightsrestrictedAccess
dc.sourceInorganica Chimica Acta
dc.titleStereospecific ligands and their complexes. Part XV. Synthesis, characterization and cytotoxicity of novel platinum(IV) complexes with some esters of ethylenediamine-N, N' N′ -di-S, S-(2,2′ -dibenzyl)acetic acid. Crystal structure of O, O′ -dipropyl-ethylenediamine -N, N′ -di-S, S-(2,2′ -dibenzyl)acetate dihydrochloride
dc.typearticle

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