Stereospecific ligands and their complexes. Part XV. Synthesis, characterization and cytotoxicity of novel platinum(IV) complexes with some esters of ethylenediamine-N, N' N′ -di-S, S-(2,2′ -dibenzyl)acetic acid. Crystal structure of O, O′ -dipropyl-ethylenediamine -N, N′ -di-S, S-(2,2′ -dibenzyl)acetate dihydrochloride
dc.contributor.author | Dimitrijević D. | |
dc.contributor.author | Glocrossed D Signović V. | |
dc.contributor.author | Radic G. | |
dc.contributor.author | García-Granda, Santiago | |
dc.contributor.author | Menéndez-Taboada L. | |
dc.contributor.author | Milovanovic, Marija | |
dc.contributor.author | Volarevic, Vladislav | |
dc.contributor.author | Arsenijevic, Nebojsa | |
dc.contributor.author | Bogdanovic, Goran A. | |
dc.contributor.author | Trifunović, Srećko | |
dc.date.accessioned | 2021-04-20T15:45:13Z | |
dc.date.available | 2021-04-20T15:45:13Z | |
dc.date.issued | 2013 | |
dc.description.abstract | The synthesis of ethylenediamine-N,N′'-di-S,S-(2,2′'-dibenzyl) acetic acid (H2-S,S-eddba) and its ethyl-, propyl-, butyl- esters (R2-S,S-eddba) are reported here. The esters were used for synthesis of the corresponding platinum(IV) complexes, [PtCl4(R 2-S,S-eddba)]. The compounds were characterized by elemental analysis, infrared, 1H and 13C NMR spectroscopy. The structure of propyl ester of H2-S,S-eddba was confirmed by single-crystal X-ray analysis. All [PtCl4(R2-S,S-eddba)] complexes displayed significantly higher in vitro cytotoxicity in comparison to cisplatin. © 2013 Published by Elsevier B.V. | |
dc.identifier.doi | 10.1016/j.ica.2013.03.039 | |
dc.identifier.issn | 0020-1693 | |
dc.identifier.scopus | 2-s2.0-84877087811 | |
dc.identifier.uri | https://scidar.kg.ac.rs/handle/123456789/10438 | |
dc.rights | restrictedAccess | |
dc.source | Inorganica Chimica Acta | |
dc.title | Stereospecific ligands and their complexes. Part XV. Synthesis, characterization and cytotoxicity of novel platinum(IV) complexes with some esters of ethylenediamine-N, N' N′ -di-S, S-(2,2′ -dibenzyl)acetic acid. Crystal structure of O, O′ -dipropyl-ethylenediamine -N, N′ -di-S, S-(2,2′ -dibenzyl)acetate dihydrochloride | |
dc.type | article |
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