Synthesis, cytotoxic activity, and thermal studies of novel N-[(1,3-diphenylpyrazol-4-yl)methyl] α-amino acids
| dc.contributor.author | Joksović, Milan | |
| dc.contributor.author | Bogdanovic, Gordana | |
| dc.contributor.author | Kojić, Vesna | |
| dc.contributor.author | Mészáros Szécsényi, Katalin | |
| dc.contributor.author | Leovac V. | |
| dc.contributor.author | Jakimov, Dimitar | |
| dc.contributor.author | Trifunović, Snežana | |
| dc.contributor.author | Marković, Violeta | |
| dc.contributor.author | Joksović, Ljubinka | |
| dc.date.accessioned | 2021-04-20T15:08:27Z | |
| dc.date.available | 2021-04-20T15:08:27Z | |
| dc.date.issued | 2010 | |
| dc.description.abstract | (Chemical Equation Presented) New N-[(1,3-diphenylpyrazol-4-yl)methyl]a- amino acids (1a-i) have been synthesized and tested in vitro for their antiproliferative activity against human myelogenous leukemia K562, colon adenocarcinoma HT-29, cervix carcinoma HeLa, and normal fetal lung fibroblasts, MRC-5. Compounds derived from both phenylalanine enantiomer precursors appeared to be the most active against myelogenous leukemia K562 cell lines with a high cytotoxic potential. © 2010 HeteroCorporation. | |
| dc.identifier.doi | 10.1002/jhet.400 | |
| dc.identifier.issn | 0022-152X | |
| dc.identifier.scopus | 2-s2.0-77954598700 | |
| dc.identifier.uri | https://scidar.kg.ac.rs/handle/123456789/10201 | |
| dc.rights | restrictedAccess | |
| dc.source | Journal of Heterocyclic Chemistry | |
| dc.title | Synthesis, cytotoxic activity, and thermal studies of novel N-[(1,3-diphenylpyrazol-4-yl)methyl] α-amino acids | |
| dc.type | article |
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